Panels (a) and (b): Charged particle $v_{4,22}$ (left) and $\rho_{4,22}$ (right) as a function of centrality in Xe$-$Xe and Pb$-$Pb collisions at $\sqrt{s_{\rm NN}}=5.44$ TeV and $\sqrt{s_{\rm NN}}=5.02$ TeV, respectively. Panels (c) and (d): Ratio between Xe$-$Xe and Pb$-$Pb $v_{4,22}$ (left) and $\rho_{4,22}$ (right). Statistical and systematical uncertainties are shown as vertical lines and grey boxes, respectively. The measurements are compared with IP-Glasma+MUSIC+UrQMD calculations to constrain the $\beta_2$ and $a_0$ parameters of $^{129}$Xe nuclei. The thickness of the bands represent statistical uncertainties.